A SYSTEMATIC AND COMPREHENSIVE REVIEW ON CURRENT UNDERSTANDING OF THE PHARMACOLOGICAL ACTIONS, MOLECULAR MECHANISMS, AND CLINICAL IMPLICATIONS OF THE GENUS EUCALYPTUS

Background: The interest in the use of Eucalyptus genus members, in parallel with preclinical studies has been steadily growing over the last few decades in the field of pharmaceuticals, agriculture, cosmetics, food, etc.Eucalyptol (1,8-cineole or cineole), the main terpenoid constituent in Eucalyptus species, has been studied in both preclinical a

Severe, glucocorticoid-resistant asthma comprises 5-7% of patients with asthma.IL-17 is a biomarker of severe asthma, and the adoptive transfer of Th17 cells in mice is sufficient to induce glucocorticoid-resistant allergic airway disease.Nitrogen dioxide (NO2) is an environmental toxin that correlates with asthma severity, exacerbation, and risk o